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1.
Aging Ment Health ; 27(11): 2257-2266, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37561088

RESUMO

OBJECTIVES: This study examined the association between hearing impairment and depression, focusing on the role of restricted social engagement as a mediator and whether the mediating relationship differed between midlife individuals (45-64) and older adults (65+). METHODS: Individuals aged 45 and older from the cross-sectional National Health and Nutrition Examination Survey 2017-2018 were analyzed (N = 3,020). A multiple-group path analysis was conducted to compare midlife individuals (n = 1,774) and older adults (n = 1,246). RESULTS: The results indicated that among U.S. adults aged 45 or older, 12.3% reported having serious difficulty hearing (21.2% among older adults vs. 7.4% among midlife adults). In both age groups, significant direct relationship between hearing impairment and depression, as well as indirect relationship via social participation restriction, were found. However, a significant difference was found in the relationship between restricted social participation and depression by age group (i.e. moderated mediation): The coefficient was greater among midlife adults than among older adults (Δbmidlife-older=1.109-0.383 = 0.726, p<.001). CONCLUSION: These findings highlight that adverse psychosocial effects of hearing impairment are also an important concern for midlife adults. As the importance of social engagement was greater among midlife adults with hearing impairment, age-specific interventions should be adopted to reduce depression associated with hearing impairment.


Assuntos
Perda Auditiva , Participação Social , Humanos , Idoso , Inquéritos Nutricionais , Estudos Transversais , Depressão/epidemiologia , Depressão/psicologia , Perda Auditiva/epidemiologia
2.
Health Educ Behav ; 50(3): 382-393, 2023 06.
Artigo em Inglês | MEDLINE | ID: mdl-36412206

RESUMO

BACKGROUND: Receiving timely health screening is associated with important public health benefits among older adults. By focusing on the role of social relationships, the present study was aimed at examining longitudinal trajectories of health screening use among older adults in Korea, whose universal health care system provides free-of-charge health screening. METHODS: A nationally representative sample of 3,575 individuals aged 65 or older from wave one of the Korean Longitudinal Study of Aging (2006) was followed for 10 years (up to Wave 6, 2016). Mixed-effect logit models were used to investigate how an older adult's social relationship characteristics (i.e., household composition, financial support from family, social group participation, and the frequency of contact with friends or relatives) were associated with their trajectories of participation in the national health screening program. RESULTS: Despite the low financial burden, only 49.7% of older adults in Korea reported receiving the recommended health screening at the baseline. Although the probability of receiving recommended health screening increased over the 10-year study period, the trajectories were significantly different by an older adult's social relationship characteristics. All four social relationship characteristics were significantly associated with receiving health screening. However, those with more frequent social contacts and those who participated in social groups showed steeper increases in the probability of receiving health screening (i.e., significant interaction with time). CONCLUSIONS: This study highlights the importance of social relationships and intervention approaches that accommodate socially isolated older adults to facilitate their timely receipt of recommended preventive care.


Assuntos
População do Leste Asiático , Relações Interpessoais , Aceitação pelo Paciente de Cuidados de Saúde , Idoso , Humanos , Envelhecimento , Estudos Longitudinais , República da Coreia
3.
J Racial Ethn Health Disparities ; 9(5): 1976-1989, 2022 10.
Artigo em Inglês | MEDLINE | ID: mdl-34448123

RESUMO

OBJECTIVES: Although Medicare is a vital source of health insurance coverage for older Americans, little is known about Medicare enrollment among older Asians. This study aimed to examine heterogeneity in Medicare enrollment across the six largest subgroups of Asian Americans (Chinese, Japanese, Filipino, Indian, Korean, and Vietnamese), in relation to their citizenship status and labor force participation. METHODS: Data from the American Community Survey Public Use Microdata Sample (2014-2018) were analyzed for older foreign-born Asians aged 65 or older (N = 83,378). A two-level multilevel logistic regression model (states > individuals) was used to model the probabilities of Medicare enrollment, accounting for state-level residential clustering by Asian subgroup and, thus, for nonindependence among respondents from the same state. RESULTS: The results indicated a substantial amount of heterogeneity in Medicare enrollment across the six Asian subgroups. Although the overall Medicare enrollment rate was low (90.2%), the rates varied from 85.5% among Indians to 93.8% among Koreans and Japanese. Naturalized citizens and those not in the labor force were associated with greater probabilities of Medicare enrollment. However, the relative differences in the Medicare enrollment rates across the six Asian subgroups were different by individuals' naturalization status and labor force participation (i.e., significant three-way interactions). DISCUSSION: These results highlight that aggregated data cannot accurately represent Medicare and health insurance status of older Asians with different sub-ethnic backgrounds. Intragroup and intergroup differences in Medicare enrollment among foreign-born older Asians should be considered for targeted policy approaches for this group of older adults.


Assuntos
Asiático , Medicare , Idoso , Povo Asiático , Emprego , Etnicidade , Humanos , Estados Unidos
4.
Viruses ; 13(9)2021 09 14.
Artigo em Inglês | MEDLINE | ID: mdl-34578407

RESUMO

Presently, the use of convalescent plasma and hyperimmunoglobulin obtained from individuals who have recovered from coronavirus disease 2019 (COVID-19) has proved to potentially provide passive antibody-based immunity, thereby leading to several clinical trials to develop an immune-based COVID-19 treatment. However, the therapeutic efficacy of hyperimmunoglobulin in critically ill patients with COVID-19 remains unknown. On 23 October 2020, we first administered GC5131 in a compassionate-use program to critically ill patients at the Kyungpook National University, Chilgok Hospital, Korea. Since then, five more critically ill patients were treated with GC5131 in this compassionate-use program in our hospital up until 17 December 2020. We retrospectively reviewed the clinical responses of six critically ill patients diagnosed with COVID-19 who received the hyperimmunoglobulin concentrate, GC5131, which was produced by the Green Cross Corporation. After the administration of GC5131, five patients died due to an exacerbation of COVID-19 pneumonia. GC5131 was ineffective when administered to critically ill patients with COVID-19. Nevertheless, we propose that to expect a therapeutic effect from GC5131, it should be administered as early as possible to avoid the excessive inflammatory response phase in patients with severe and advanced COVID-19 infection. This step was difficult to achieve in the real world due to the time required for decision making and the process of the compassionate-use program.


Assuntos
Tratamento Farmacológico da COVID-19 , COVID-19/terapia , COVID-19/virologia , Estado Terminal , Imunoglobulinas/uso terapêutico , SARS-CoV-2/efeitos dos fármacos , Idoso , COVID-19/diagnóstico , Ensaios de Uso Compassivo , Feminino , Humanos , Imunização Passiva , Masculino , República da Coreia , Resultado do Tratamento , Soroterapia para COVID-19
5.
Thorac Cancer ; 12(6): 874-879, 2021 03.
Artigo em Inglês | MEDLINE | ID: mdl-33522072

RESUMO

BACKGROUND: To examine the impact of polymorphisms of glucose transporter 1 (GLUT1) gene on the prognosis of patients with stage III non-small cell lung cancer (NSCLC) who received radiotherapy. METHODS: Five single nucleotide polymorphisms (SNPs) (rs4658C>G, rs1385129G>A, rs3820589A>T, rs3806401A>C and rs3806400C>T) in GLUT1 gene were evaluated in 90 patients with pathologically confirmed stage III NSCLC. A total of 21 patients were treated with radiotherapy alone, 25 with sequential chemoradiotherapy, and 44 with concurrent chemoradiotherapy. The association of the genetic variations of five SNPs with overall survival (OS) and progression-free survival (PFS) was analyzed. RESULTS: Two SNPs (rs1385129 and rs3806401) were significant risk factors for OS. Three SNPs (rs1385129, rs3820589 and rs3806401) were in linkage disequilibrium. In Cox proportional hazard models, GAA haplotype was a good prognostic factor for OS (hazard ratio [HR] = 0.57, 95% confidence interval [CI]: 0.39-0.81, p = 0.002) and PFS (HR = 0.68, 95% CI: 0.47-0.99, p = 0.043), compared to variant haplotypes. The GAA/GAA diplotype was observed in 46.7% of patients; these patients showed significantly better OS (HR = 0.38, 95% CI: 0.22-0.65, p < 0.001) and PFS (HR = 0.51, 95% CI: 0.31-0.85, p = 0.009) compared to those with other diplotypes. CONCLUSIONS: These results suggest that polymorphisms of GLUT1 gene could be used as a prognostic marker for patients with stage III NSCLC treated with radiotherapy.


Assuntos
Carcinoma Pulmonar de Células não Pequenas/genética , Carcinoma Pulmonar de Células não Pequenas/radioterapia , Transportador de Glucose Tipo 1/genética , Neoplasias Pulmonares/genética , Neoplasias Pulmonares/radioterapia , Idoso , Idoso de 80 Anos ou mais , Carcinoma Pulmonar de Células não Pequenas/metabolismo , Carcinoma Pulmonar de Células não Pequenas/patologia , Feminino , Variação Genética , Transportador de Glucose Tipo 1/metabolismo , Humanos , Neoplasias Pulmonares/metabolismo , Neoplasias Pulmonares/patologia , Masculino , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Polimorfismo de Nucleotídeo Único , Prognóstico
6.
J Appl Gerontol ; 40(4): 365-376, 2021 04.
Artigo em Inglês | MEDLINE | ID: mdl-31976785

RESUMO

This study investigated the relationships among age, labor force participation, and citizenship status in relation to non-Medicare enrollment among individuals aged 65 years or older. Two-level multilevel modeling (states > individuals) with a nationally representative sample of 566,003 individuals was conducted to control for state-level variations in non-Medicare enrollment rates. Among those aged 65 to 66 years, 11.2% were non-Medicare enrollees nationwide. However, analyses indicated significant differences in non-Medicare enrollment rates by age, labor force participation, citizenship status, and state of residence. Moreover, the relationship between labor force participation and age was different between U.S. citizens and noncitizens (i.e., a significant three-way interaction). Specifically, labor force participation was associated with greater probabilities of non-Medicare enrollment among U.S. citizens aged between 65 and 69 years, although the opposite was true among noncitizens. While reasons for non-Medicare enrollment appear voluntary for some older adults (i.e., employment), some associated factors indicate subpopulations of vulnerable non-Medicare enrollees (i.e., noncitizens, aged 70+).


Assuntos
Emprego , Idoso , Humanos , Estados Unidos
7.
J Gerontol Soc Work ; 63(8): 850-863, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33043850

RESUMO

This study examined how restricted social participation mediates the relationship between chronic illness and psychological distress among community-dwelling older adults. Additionally, the use of the Internet for health care was tested as a moderator to examine whether the relationship between limited social participation and psychological distress differs. Using the multiple-group path analysis approach, 16,032 community-dwelling older adults (65+) from the National Health Interview Survey were analyzed. The findings show that 32.2% suffered from chronic illnesses that limited their daily activities, and 26% reported social participation restrictions to some degree. While having chronic illnesses was associated with greater psychological distress, the association was also through increased social participation restriction (mediation). Furthermore, differences in mediation were found between health information technology users and nonusers (moderated mediation). In contrast to the hypothesis, the adverse relationship between limited social participation and psychological distress was stronger among users, although chronic conditions were associated with greater social participation restrictions among nonusers. The findings suggest that with proper accommodations and interventions that aim to increase the social participation of community-dwelling older adults, the disadvantageous effects of chronic conditions on psychological distress could be ameliorated. Moreover, the importance of such interventions is greater among health information technology users.


Assuntos
Doença Crônica/psicologia , Angústia Psicológica , Participação Social/psicologia , Atividades Cotidianas , Idoso , Idoso de 80 Anos ou mais , Humanos , Vida Independente , Masculino , Informática Médica/estatística & dados numéricos
8.
Am J Med Sci ; 360(4): 383-391, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32690276

RESUMO

BACKGROUND: Risk stratification is important for the management of community-acquired pneumonia (CAP). The present study aimed to investigate the clinical impact of N-terminal prohormone of brain natriuretic peptide (NT-proBNP) on prognosis and to identify clinical characteristics associated with NT-proBNP elevation in CAP patients. METHODS: This retrospective study included patients hospitalized for CAP at a tertiary referral center and who underwent measurement plasma NT-proBNP levels. Based on 30-day mortality, patients (n = 1,821) were divided into 2 groups, survivors (n = 150) and nonsurvivors (n = 1,671), and clinical and laboratory findings were compared. RESULTS: In multivariate analysis, blood levels of NT-proBNP (>942.5 pg/mL), albumin (<3.3 g/dL), and troponin I (>0.018 ng/mL) independently predicted 30-day mortality. Of these blood biomarkers, NT-proBNP exhibited the highest C-statistic, followed by albumin. NT-proBNP level/CURB-65 score and NT-proBNP level/pneumonia severity index (PSI) class exhibited significantly higher C-statistics than CURB-65 score and PSI class alone, respectively. The 3-test combinations of CURB-65 score/NT-proBNP level/albumin level and PSI class/NT-proBNP level/albumin level exhibited significantly higher C-statistics than the 2-test combinations. NT-proBNP elevation was associated with increased age, heart disease and chronic kidney disease and NT-proBNP levels only weakly or moderately correlated with other blood biomarkers. CONCLUSIONS: NT-proBNP level was a useful marker for the prediction of 30-day mortality in patients hospitalized with CAP, and provided additional prognostic value to PSI or CURB-65 alone.


Assuntos
Peptídeo Natriurético Encefálico/sangue , Fragmentos de Peptídeos/sangue , Pneumonia/sangue , Pneumonia/mortalidade , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Biomarcadores/sangue , Infecções Comunitárias Adquiridas/sangue , Infecções Comunitárias Adquiridas/mortalidade , Feminino , Humanos , Masculino , Análise Multivariada , Valor Preditivo dos Testes , Estudos Retrospectivos , Índice de Gravidade de Doença
9.
Aging Ment Health ; 24(5): 758-764, 2020 05.
Artigo em Inglês | MEDLINE | ID: mdl-30618275

RESUMO

Objectives: This study examined the relationship between body mass index (BMI) and trajectories of cognitive decline among older Korean adults.Methods: Participants were a nationally representative sample of 5126 Korean adults aged 60 or older from the Korean Longitudinal Study of Aging (KLoSA: 2006-2014). The main outcome variable, cognitive function, was measured with the Korean Mini-Mental State Examination (K-MMSE). According to the BMI values, respondents were divided into four groups at each wave: underweight (<18.5 kg/m2), healthy weight (18.5-22.9 kg/m2), overweight (23.0-24.9 kg/m2), and obese (≥25.0 kg/m2). Growth curve modeling was used to analyze the relationship of interest.Results: The growth curve modeling revealed that, regardless of BMI values, cognitive functioning declined as participants aged, and the rate of cognitive decline accelerated with age. After adjusting for all covariates, older Korean adults who were underweight displayed steeper declines in cognitive functioning, compared to those with a healthy weight. Conversely, overweight or obese older adults showed a much slower cognitive decline as they aged, after adjusting for covariates.Conclusion: Compared to people with a healthy BMI, people with a low BMI may be at risk for cognitive dysfunction, whereas a high BMI could function as a protective factor for cognitive dysfunction in older adulthood. Future research examining the mechanism for these trajectories are needed. Implications for research and clinical practice are discussed.


Assuntos
Disfunção Cognitiva , Adulto , Idoso , Índice de Massa Corporal , Cognição , Disfunção Cognitiva/epidemiologia , Humanos , Estudos Longitudinais , República da Coreia/epidemiologia
10.
Disabil Health J ; 11(3): 374-381, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-29307574

RESUMO

BACKGROUND: Arthritis is the most common cause of disability among U.S. adults. OBJECTIVE: This study examined how the onset of arthritis-attributable disability affects midlife individuals. METHODS: Using the 2014-2015 National Health Interview Survey, this study compared three groups of midlife adults (ages 50-64): individuals without any physical limitations (n = 13,779); individuals with early-onset arthritis that has limited their functioning for more than 20 years (n = 330); and individuals suffering from late-onset arthritis-attributable disability for less than five years (n = 299), in relation to five domains in the International Classification of Functioning, Disability and Health (ICF) framework. Stata's SVY procedures were used for bivariate and multivariate comparisons. RESULTS: Compared with the two groups with arthritis-attributable disability, midlife adults without disability were more likely to be married, college educated, high income, and employed. They also reported considerably lower levels of financial worries, barriers to healthcare access, and psychological distress (p < .05). However, although midlife adults with arthritis-attributable disability in both groups displayed similar vulnerability in all domains, the two groups were different in significant ways. For example, compared with those with early-onset disability, midlife adults with late-onset arthritis-related disability were more likely to worry about their finances in general, while they experienced lower levels of social participation restrictions and activity limitations in some functioning areas (p < .05). CONCLUSIONS: This study clearly indicates how experiencing arthritis-attributable disability on top of aging is challenging for midlife adults and how considering the onset of disability is important for practitioners and researchers.


Assuntos
Atividades Cotidianas , Artrite/complicações , Pessoas com Deficiência , Renda , Qualidade de Vida , Participação Social , Estresse Psicológico , Fatores Etários , Idade de Início , Envelhecimento , Ansiedade , Artrite/psicologia , Avaliação da Deficiência , Pessoas com Deficiência/psicologia , Emprego , Feminino , Declarações Financeiras , Necessidades e Demandas de Serviços de Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Fatores Socioeconômicos , Estados Unidos
11.
Health Educ Behav ; 45(4): 616-624, 2018 08.
Artigo em Inglês | MEDLINE | ID: mdl-29117725

RESUMO

Using 2-year panel data, this study examined (1) whether experiencing financial hardship associated with out-of-pocket medical expenditures affected delaying/missing necessary health care in the following year; (2) whether such financial hardship mediated the effects of predisposing, enabling, and need characteristics on timely health care access (i.e., significant indirect effects); and (3)whether such mediating effects are different by chronic health status (i.e., moderated mediation) among U.S. adults. The 2011 National Health Interview Survey was linked to the 2012 Medical Expenditure Panel Survey. The sample includes 8,993 adults aged between 26 and 64 years. Among them, 1,089 reported having at least one chronic health condition that had caused activity limitations. Multiple-group path analysis was conducted using Mplus 7.2. Approximately 35% experienced financial difficulties paying medical bills, including 28% who were currently paying off medical debts. Almost 14% of the respondents reported delayed/missed necessary medical treatments. In addition to direct effects, predisposing, enabling, and need factors affected access to care indirectly via financial hardship, although significant moderated mediation was found by chronic health status. However, different from the Andersen's behavioral model of health service utilization, the effect of financial hardship due to medical bills as a barrier to the timely use of necessary health services was not smaller among adults with chronic health conditions. Policy alternatives should be explored to provide affordable financing programs and adequate safety net health services to reduce the financial burden of health care for those who are financially vulnerable, especially those suffering from chronic health conditions.


Assuntos
Gastos em Saúde/estatística & dados numéricos , Nível de Saúde , Seguro Saúde/estatística & dados numéricos , Aceitação pelo Paciente de Cuidados de Saúde/estatística & dados numéricos , Pobreza , Adulto , Feminino , Comportamentos Relacionados com a Saúde , Inquéritos Epidemiológicos , Humanos , Masculino , Pessoa de Meia-Idade , Estados Unidos
12.
Popul Health Manag ; 21(3): 235-244, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28953421

RESUMO

This study aimed to examine how states' Medicaid expansion affected insurance status and access to health care among low-income expansion state residents in 2015, the second year of the expansion. Data from the 2012 and 2015 Behavioral Risk Factor Surveillance System were linked to state-level data. A nationally representative sample of 544,307 adults (ages 26-64 years) from 50 states and Washington, DC were analyzed using multilevel modeling. The results indicate substantial increases in health care access between 2012 and 2015 among low-income adults in Medicaid expansion states. The final conditional multilevel models with low-income adults who had income at or below 138% of the poverty line indicate that, after controlling for individual- and state-level covariates, those who resided in the Medicaid expansion states were more likely to have health insurance (OR = 1.97, P < .001), have a usual source of care (OR = 1.37, P < .01), and receive a routine checkup (OR = 1.24, P < .01), and were less likely to not see a doctor because of cost (OR = 0.66, P < .001) compared with low-income residents in non-expansion states in 2015. Moreover, the significant interaction terms indicate that adults living in non-expansion states with income below 100% of the poverty line are the most vulnerable compared with their counterparts in expansion states and with those with income between 100%-138% of the poverty line. This study demonstrates that state-level Medicaid expansion improved health care access among low-income US residents. However, residents with income below 100% of the poverty line in non-expansion states were disproportionately negatively affected by states' decision to not expand Medicaid coverage.


Assuntos
Acessibilidade aos Serviços de Saúde , Medicaid , Patient Protection and Affordable Care Act , Adulto , Feminino , Acessibilidade aos Serviços de Saúde/economia , Acessibilidade aos Serviços de Saúde/estatística & dados numéricos , Humanos , Masculino , Medicaid/economia , Medicaid/estatística & dados numéricos , Pessoas sem Cobertura de Seguro de Saúde , Pessoa de Meia-Idade , Patient Protection and Affordable Care Act/economia , Patient Protection and Affordable Care Act/estatística & dados numéricos , Pobreza , Estados Unidos
13.
J Aging Health ; 29(2): 222-246, 2017 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26944806

RESUMO

OBJECTIVE: This study examined out-of-pocket premium burden of mid-life Asian Americans by comparing six sub-groups of Asians after controlling for geographic clustering at the county and state levels. METHOD: The 2007-2011 National Health Interview Survey was linked to community-level data and analyzed for 4,628 Asians (ages 50-64), including 697 Asian Indians, 1,125 Chinese, 1,393 Filipinos, 434 Japanese, 524 Koreans, and 455 Vietnamese. Non-Hispanic Whites were included as a comparison group ( n = 48,135). Three-level multilevel modeling (state > county > individual) was conducted. RESULTS: Koreans and Vietnamese were found as vulnerable sub-groups considering their lower private health insurance rates and higher uninsured rates. Among those with private insurance, Asians, specifically Filipinos, paid significantly less than non-Hispanic Whites. Moderate but significant variations in the county- and state-level variance in out-of-pocket premiums were found, especially among mid-life Asians. DISCUSSION: This study demonstrates the importance of examining within-group heterogeneity and geographic variations in understanding premium burden among mid-life Asians.


Assuntos
Asiático , Financiamento Pessoal , Seguro Saúde/economia , Etnicidade , Feminino , Financiamento Pessoal/estatística & dados numéricos , Humanos , Entrevistas como Assunto , Masculino , Pessoa de Meia-Idade , Pesquisa Qualitativa
14.
Int J Health Serv ; 46(4): 693-711, 2016 10.
Artigo em Inglês | MEDLINE | ID: mdl-27496545

RESUMO

UNLABELLED: Healthy People 2020 in the United States highlights timely access to necessary health care as a major factor that can reduce health-related disparities. This study examined the prevalence of delaying/missing necessary health care because of cost among foreign-born adults (26+ years old) in the United States by their region of origin, after controlling for geographic clustering at the county and state levels. METHODS: Using the pooled 2007-2011 National Health Interview Survey and linked state/county-level data, this study analyzed data on 61,732 foreign-born adults from nine regions of birth. Three-level multilevel modeling (state > county > individual) was conducted. The age-adjusted percentages of foreign-born adults who delayed/missed necessary health care because of cost varied by region of birth, ranging from 7.0% (Southeast Asia) and 11.9% (Europe) to 15.5% (Mexico/Central America/Caribbean) and 16.7% (the Middle East). However, after controlling for geographic clustering and other individual-level covariates (e.g., insurance), adults from Mexico/Central America/Caribbean were less likely to delay or not receive necessary care compared to their counterparts from all other parts of the world except for those from Asian regions. This study implies that disparities can be reduced if some known risk factors (e.g., insurance) are improved among foreign-born adults.


Assuntos
Emigrantes e Imigrantes , Custos de Cuidados de Saúde , Acessibilidade aos Serviços de Saúde , Necessidades e Demandas de Serviços de Saúde , Disparidades em Assistência à Saúde , Adulto , Idoso , Ásia/etnologia , Europa (Continente)/etnologia , Feminino , Humanos , Masculino , México/etnologia , Pessoa de Meia-Idade , Estados Unidos
15.
Pediatr Int ; 58(7): 616-9, 2016 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-27460398

RESUMO

Pleural empyema is rare in neonates, and treatment with systemic antibiotics and tube drainage may fail because of the thick viscous fluid, bacterial products with fibrin deposition, and multiple loculations. Intrapleural fibrinolytic therapy with urokinase is an effective and non-invasive treatment option that avoids surgical intervention, although its use in neonates has not been studied extensively. In this report, we describe the case of a 13-day-old male neonate with Escherichia coli sepsis and pneumonia, which rapidly progressed to parapneumonic effusion and pleural empyema. After inadequate response to i.v. antibiotics and chest tube drainage, the patient was successfully treated with intrapleural urokinase.


Assuntos
Empiema Pleural/tratamento farmacológico , Ativador de Plasminogênio Tipo Uroquinase/administração & dosagem , Empiema Pleural/diagnóstico , Humanos , Recém-Nascido , Injeções , Masculino , Pleura , Tomografia Computadorizada por Raios X , Ultrassonografia
16.
J Cardiovasc Ultrasound ; 24(1): 40-7, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-27081443

RESUMO

BACKGROUND: In adults, tissue Doppler imaging (TDI) is a recommended component of routine echocardiography. However, TDI velocities are less accepted in pediatrics, due to their strong variability and age dependence in children. This study examines the distribution of myocardial tissue Doppler velocities in healthy children to assess the effect of age with cardiac growth on the various echocardiographic measurements. METHODS: Total 144 healthy children were enrolled in this study. They were recruited from the pediatric outpatient clinic for routine well-child visits. The statistical relationships between age and TDI values were analyzed. Also, the statistical relationships between body surface area (BSA) and TDI values, left ventricle end-diastolic dimension (LVEDD) and TDI values were analyzed. Also, we conducted multivariate analysis of cardiac growth parameters such as, age, BSA, LVEDD and TDI velocity data. RESULTS: All of the age, BSA, and LVEDD had positive correlations with deceleration time (DT), pressure half-time (PHT), peak early diastolic myocardial velocity, peak systolic myocardial velocity, and had negative correlations with peak late diastolic velocity (A) and the ratio of trans-mitral inflow velocity to early diastolic velocity of mitral annulus (E/E'). In the multivariate analysis, all of the age, BSA, and LVEDD had positive correlations with DT, PHT, and negative correlations with A and E/E'. CONCLUSION: The cardiac growth parameters related alterations of E/E' may suggest that diastolic myocardial velocities are cardiac growth dependent, and diastolic function has positive correlation with cardiac growth in pediatric group. This cardiac growth related myocardial functional variation would be important for assessment of cardiac involvement either in healthy and sick child.

17.
Psychiatr Q ; 87(4): 675-688, 2016 12.
Artigo em Inglês | MEDLINE | ID: mdl-26910461

RESUMO

Using the 2004-2007 Medical Expenditure Panel Survey data that are linked to county-level data from the Area Health Resources Files, this study examined whether the healthy immigrant effect applies to mental health of foreign-born older adults. Additionally, testing a protective ethnic density effect on older foreign-born individuals' mental health, this study examined how the percentage of foreign-born population in the county affected the relationship between older adults' immigration status (U.S.-nativity and length of residence in the U.S.) and their mental health status. The sample included 29,011 individuals (level-1) from 920 counties (level-2) across 50 states and D.C. Using the Mental Component Summary of the Short-Form 12, the Kessler Index (K-6), and the Patient Health Questionnaire (PHQ-2), U.S.-born individuals (n = 24,225), earlier immigrants (≥15 years in the U.S.; n = 3866), and recent immigrants (<15 years in the U.S.; n = 920) were compared. The results indicate that recent immigrants showed worse mental health on all three measures compared with U.S.-born individuals and on the K-6 and PHQ-2 compared with earlier immigrants. Higher county-level foreign-born densities were associated with worse mental health status of individuals. However, the significant interactions found in the full conditional multilevel models indicated that the high foreign-born density functioned as a risk factor for worse mental health only among recent immigrants but not among the U.S.-born. In conclusion, the results revealed the vulnerability of older recent immigrants, especially those living in the counties with high foreign-born densities.


Assuntos
Ansiedade/psicologia , Depressão/psicologia , Emigrantes e Imigrantes/psicologia , Saúde Mental , Densidade Demográfica , Estresse Psicológico/psicologia , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Características de Residência , Fatores de Tempo , Estados Unidos
18.
J Ment Health ; 25(4): 291-296, 2016 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-26654582

RESUMO

BACKGROUND AND AIMS: Little is known about the incremental cost burden associated with treating comorbid health conditions among people with severe mental illness (SMI). This study compares the extent to which each individual medical condition increases healthcare expenditures between people with SMI and people without mental illness. METHODS: Data were obtained from the 2011 Medical Expenditure Panel Survey (MEPS; N = 17 764). Mental illness and physical health conditions were identified through ICD-9 codes. Guided by the Andersen's behavioral model of health services utilization, generalized linear models were conducted. RESULTS: Total healthcare expenditures among individuals with SMI were approximately 3.3 times greater than expenditures by individuals without mental illness ($11 399 vs. $3449, respectively). Each additional physical health condition increased the total healthcare expenditure by 17.4% for individuals with SMI compared to the 44.8% increase for individuals without mental illness. CONCLUSIONS: The cost effect of having additional health conditions on the total healthcare expenditures among individuals with SMI is smaller than those individuals without mental illness. Whether this is due to limited access to healthcare for the medical problems or better coordination between medical and mental health providers, which reduces duplicated medical procedures or visits, requires future investigation.


Assuntos
Efeitos Psicossociais da Doença , Gastos em Saúde , Transtornos Mentais/economia , Transtornos Mentais/epidemiologia , Adulto , Comorbidade , Feminino , Humanos , Masculino , Transtornos Mentais/complicações , Índice de Gravidade de Doença , Estados Unidos
19.
Soc Work Health Care ; 54(7): 669-85, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26317767

RESUMO

This study compared three age groups of uninsured adults, young (26-44), middle-aged (45-64), and older (65≥), to examine heterogeneity of the uninsured. The pooled 2000-2007 Medical Expenditure Panel Survey was analyzed (N = 22,246). The findings demonstrated that the three groups were very different regarding their individual characteristics, health service utilization, and health beliefs. Compared with uninsured young adults, uninsured middle-aged individuals reported worse health statuses, paid higher out-of-pocket medical expenditures, and had more positive attitudes toward insurance and health care. Considering the policy goals of the Affordable Care Act, understanding the uninsured by age will facilitate targeted interventions to decrease the number of uninsured.


Assuntos
Conhecimentos, Atitudes e Prática em Saúde , Acessibilidade aos Serviços de Saúde/estatística & dados numéricos , Serviços de Saúde/estatística & dados numéricos , Pessoas sem Cobertura de Seguro de Saúde/psicologia , Satisfação do Paciente , Adulto , Fatores Etários , Idoso , Feminino , Financiamento Pessoal/estatística & dados numéricos , Acessibilidade aos Serviços de Saúde/economia , Nível de Saúde , Humanos , Masculino , Pessoa de Meia-Idade , Patient Protection and Affordable Care Act , Fatores Socioeconômicos
20.
Gerontologist ; 55(5): 735-47, 2015 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-24451897

RESUMO

PURPOSE OF THE STUDY: This study examined patient satisfaction among community-dwelling older adults by their citizenship and nativity statuses. Since the welfare reform of 1996, citizenship has been an important factor in determining health care access among foreign-born individuals. Little is known regarding how the perceived satisfaction of older noncitizens compares with that of U.S.-born and naturalized citizens and how it is affected by county-level contextual characteristics. DESIGN AND METHODS: The 2000-2007 Medical Expenditure Panel Survey and linked Area Resource File were analyzed for 27,383 individuals (65+). Two dimensions of satisfaction (perceived access and ease of access) were examined using the Consumer Assessment of Health Plans Survey. Multilevel models were conducted using STATA. RESULTS: After both individual- and county-level covariates were controlled for, noncitizens were less likely to agree that their providers had spent enough time with them (p = .03) or had sufficiently explained treatment (p = .01) compared with U.S.-born citizens. Noncitizens' overall ratings of their providers were also lower (p < .001). Among those reported needs, noncitizens reported greater difficulties in accessing acute care (p < .001), routine care (p < .001), and specialty care (p = .009). In these models, some county-level characteristics (e.g., % of foreign-born individuals) were negatively associated with individual-level satisfaction. Interestingly, noncitizens from counties with high densities of foreign-born populations had higher overall satisfaction levels than did their U.S.-born counterparts (i.e., interaction effect). IMPLICATIONS: Guided by the expanded Andersen model, this study demonstrates the importance of considering both individual- and county-level contextual characteristics to accurately understand older noncitizens' access to health care and patient satisfaction.


Assuntos
Emigrantes e Imigrantes/psicologia , Acessibilidade aos Serviços de Saúde/estatística & dados numéricos , Serviços de Saúde/estatística & dados numéricos , Disparidades em Assistência à Saúde/etnologia , Satisfação do Paciente , Satisfação Pessoal , Idoso , Idoso de 80 Anos ou mais , Emigrantes e Imigrantes/estatística & dados numéricos , Feminino , Pesquisas sobre Atenção à Saúde , Gastos em Saúde , Humanos , Masculino , Análise Multinível , Grupos Raciais/etnologia , Grupos Raciais/estatística & dados numéricos , Características de Residência , Seguridade Social/economia , Fatores Socioeconômicos , Estados Unidos
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